Endocrine Abstracts

Introduction: Bisphosphonates are widely used to treat osteoporosis, hypercalcemia of malignancy and multiple myeloma. Albeit rare, bisphosphonate induced osteonecrosis of jaw is serious adverse event which significantly affects quality of life. Clinical presentation includes gingival ulceration, exposed necrotic bone in the oral cavity. In severe cases it may cause spontaneous pain, tooth mobility and pathological fractures.Case Report: A 70-year-old ma...

Background: Hirsutism is a common and disturbing complaint among women attending endocrine clinics. It is caused by androgen excess and when severe, might progress to virilization. Virilizing adrenal tumors are a rare cause of hirsutism.Case presentation: A 14 year old girl presented with primary amenorrhea, poor breast development (Tanner stage B1), hirsutism (Ferriman-gallwey score, FGS of 12/36) clitoromegaly (clitoral index >200 mm2). ...